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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: INPP5F All Species: 20.61
Human Site: S192 Identified Species: 45.33
UniProt: Q9Y2H2 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9Y2H2 NP_055752.1 1132 128407 S192 T N S V Q R Q S T G E R D G R
Chimpanzee Pan troglodytes XP_508074 1133 128517 S192 T N S V Q R Q S T G E R D G R
Rhesus Macaque Macaca mulatta XP_001099262 1133 128209 S192 T N S V Q R Q S T G E R D G R
Dog Lupus familis XP_535034 1137 128796 S196 T N S V Q R Q S A G E R D P R
Cat Felis silvestris
Mouse Mus musculus Q8CDA1 1132 127590 S192 T N S V Q R Q S T G E R D G R
Rat Rattus norvegicus Q9ES21 587 67020
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514944 750 86937
Chicken Gallus gallus XP_421792 1126 127898 S192 T N S V Q R Q S A C E K T D L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A8E7C5 1120 126036 G192 T N T V Q R Q G E L G K S D Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392092 1118 126657 C209 T N S L Q R L C A T E S Q Y N
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_789035 2077 234760 H225 T N S I Q R H H T H K G A G Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 97.9 91.8 N.A. 90.5 21.2 N.A. 62.1 82.9 N.A. 71.2 N.A. N.A. 35.3 N.A. 26.6
Protein Similarity: 100 99.9 99.1 95 N.A. 94.5 33.8 N.A. 64.4 90.2 N.A. 82.8 N.A. N.A. 53.6 N.A. 38.4
P-Site Identity: 100 100 100 86.6 N.A. 100 0 N.A. 0 60 N.A. 40 N.A. N.A. 40 N.A. 46.6
P-Site Similarity: 100 100 100 86.6 N.A. 100 0 N.A. 0 66.6 N.A. 60 N.A. N.A. 46.6 N.A. 60
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 28 0 0 0 10 0 0 % A
% Cys: 0 0 0 0 0 0 0 10 0 10 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 46 19 0 % D
% Glu: 0 0 0 0 0 0 0 0 10 0 64 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 10 0 46 10 10 0 46 0 % G
% His: 0 0 0 0 0 0 10 10 0 10 0 0 0 0 0 % H
% Ile: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 10 19 0 0 0 % K
% Leu: 0 0 0 10 0 0 10 0 0 10 0 0 0 0 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 82 0 0 0 0 0 0 0 0 0 0 0 0 10 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % P
% Gln: 0 0 0 0 82 0 64 0 0 0 0 0 10 0 10 % Q
% Arg: 0 0 0 0 0 82 0 0 0 0 0 46 0 0 46 % R
% Ser: 0 0 73 0 0 0 0 55 0 0 0 10 10 0 0 % S
% Thr: 82 0 10 0 0 0 0 0 46 10 0 0 10 0 0 % T
% Val: 0 0 0 64 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _